more than okay, I would say 
Cannot think of a reason why such data leads to an error. MST and MCS produce the same problem?
The only thing I can then suggest is to test if SMOOTH runs differently than TOPO or DEFO.
Since snaphu version 2 there is an option to exclude low coherence areas or to mask out certain areas, but I see no reason why this is necessary in your case, nor does it simplify the workflow for multiply products.